Ursodeoxycholic acid inhibits intimal hyperplasia, vascular smooth muscle cell excessive proliferation, migration via blocking miR-21/PTEN/AKT/mTOR signaling pathway

Excessive migration and proliferation of vascular smooth muscle cells (VSMCs) are critical cellular events that lead to intimal hyperplasia in atherosclerosis and restenosis. In this study, we investigated the protective effects of ursodeoxycholic acid (UDCA) on intimal hyperplasia and VSMC prolifer...

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Detalles Bibliográficos
Autores principales: Huang, Rong, Huang, Yi, Zeng, Guang, Li, Mengfan, Jin, Yongzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217369/
https://www.ncbi.nlm.nih.gov/pubmed/32202193
http://dx.doi.org/10.1080/15384101.2020.1732514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217369/
https://www.ncbi.nlm.nih.gov/pubmed/32202193
http://dx.doi.org/10.1080/15384101.2020.1732514

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