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The Rho-associated kinase inhibitor fasudil can replace Y-27632 for use in human pluripotent stem cell research
Poor survival of human pluripotent stem cells (hPSCs) following freezing, thawing, or passaging hinders the maintenance and differentiation of stem cells. Rho-associated kinases (ROCKs) play a crucial role in hPSC survival. To date, a typical ROCK inhibitor, Y-27632, has been the primary agent used...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217428/ https://www.ncbi.nlm.nih.gov/pubmed/32396545 http://dx.doi.org/10.1371/journal.pone.0233057 |