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The Rho-associated kinase inhibitor fasudil can replace Y-27632 for use in human pluripotent stem cell research

Poor survival of human pluripotent stem cells (hPSCs) following freezing, thawing, or passaging hinders the maintenance and differentiation of stem cells. Rho-associated kinases (ROCKs) play a crucial role in hPSC survival. To date, a typical ROCK inhibitor, Y-27632, has been the primary agent used...

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Detalles Bibliográficos
Autores principales: So, Seongjun, Lee, Yeonmi, Choi, Jiwan, Kang, Seoon, Lee, Ji-Yoon, Hwang, Julie, Shin, Joosung, Dutton, James R., Seo, Eul-Ju, Lee, Beom Hee, Kim, Chong Jai, Mitalipov, Shoukhrat, Oh, Soo Jin, Kang, Eunju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217428/
https://www.ncbi.nlm.nih.gov/pubmed/32396545
http://dx.doi.org/10.1371/journal.pone.0233057