Early correction of synaptic long-term depression improves abnormal anxiety-like behavior in adult GluN2B-C456Y-mutant mice

Extensive evidence links Glutamate receptor, ionotropic, NMDA2B (GRIN2B), encoding the GluN2B/NR2B subunit of N-methyl-D-aspartate receptors (NMDARs), with various neurodevelopmental disorders, including autism spectrum disorders (ASDs), but the underlying mechanisms remain unclear. In addition, it...

Descripción completa

Detalles Bibliográficos
Autores principales: Shin, Wangyong, Kim, Kyungdeok, Serraz, Benjamin, Cho, Yi Sul, Kim, Doyoun, Kang, Muwon, Lee, Eun-Jae, Lee, Hyejin, Bae, Yong Chul, Paoletti, Pierre, Kim, Eunjoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217483/
https://www.ncbi.nlm.nih.gov/pubmed/32353004
http://dx.doi.org/10.1371/journal.pbio.3000717

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217483/
https://www.ncbi.nlm.nih.gov/pubmed/32353004
http://dx.doi.org/10.1371/journal.pbio.3000717

Ejemplares similares