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Early correction of synaptic long-term depression improves abnormal anxiety-like behavior in adult GluN2B-C456Y-mutant mice

Extensive evidence links Glutamate receptor, ionotropic, NMDA2B (GRIN2B), encoding the GluN2B/NR2B subunit of N-methyl-D-aspartate receptors (NMDARs), with various neurodevelopmental disorders, including autism spectrum disorders (ASDs), but the underlying mechanisms remain unclear. In addition, it...

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Detalles Bibliográficos
Autores principales:	Shin, Wangyong, Kim, Kyungdeok, Serraz, Benjamin, Cho, Yi Sul, Kim, Doyoun, Kang, Muwon, Lee, Eun-Jae, Lee, Hyejin, Bae, Yong Chul, Paoletti, Pierre, Kim, Eunjoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217483/ https://www.ncbi.nlm.nih.gov/pubmed/32353004 http://dx.doi.org/10.1371/journal.pbio.3000717

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