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Dimethyl fumarate suppresses granulocyte macrophage colony-stimulating factor–producing Th1 cells in CNS neuroinflammation

OBJECTIVE: To study the immunomodulatory effect of dimethyl fumarate (DF) on granulocyte macrophage colony-stimulating factor (GM-CSF) production in CD4(+) T cells in experimental autoimmune encephalomyelitis (EAE) and human peripheral blood mononuclear cells (PBMCs). METHODS: We collected splenocyt...

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Detalles Bibliográficos
Autores principales: Safavi, Farinaz, Thome, Rodolfo, Li, Zichen, Zhang, Guang-Xian, Rostami, Abdolmohamad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217662/
https://www.ncbi.nlm.nih.gov/pubmed/32371548
http://dx.doi.org/10.1212/NXI.0000000000000729