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Single-cell RNA-seq analysis of human CSF microglia and myeloid cells in neuroinflammation

OBJECTIVE: To identify and characterize myeloid cell populations within the CSF of patients with MS and anti-myelin oligodendrocyte glycoprotein (MOG) disorder by high-resolution single-cell gene expression analysis. METHODS: Single-cell RNA sequencing (scRNA-seq) was used to profile individual cell...

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Detalles Bibliográficos
Autores principales: Esaulova, Ekaterina, Cantoni, Claudia, Shchukina, Irina, Zaitsev, Konstantin, Bucelli, Robert C., Wu, Gregory F., Artyomov, Maxim N., Cross, Anne H., Edelson, Brian T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217663/
https://www.ncbi.nlm.nih.gov/pubmed/32371549
http://dx.doi.org/10.1212/NXI.0000000000000732