A mammalian Wnt5a–Ror2–Vangl2 axis controls the cytoskeleton and confers cellular properties required for alveologenesis

Alveolar formation increases the surface area for gas-exchange and is key to the physiological function of the lung. Alveolar epithelial cells, myofibroblasts and endothelial cells undergo coordinated morphogenesis to generate epithelial folds (secondary septa) to form alveoli. A mechanistic underst...

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Detalles Bibliográficos
Autores principales: Zhang, Kuan, Yao, Erica, Lin, Chuwen, Chou, Yu-Ting, Wong, Julia, Li, Jianying, Wolters, Paul J, Chuang, Pao-Tien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217702/
https://www.ncbi.nlm.nih.gov/pubmed/32394892
http://dx.doi.org/10.7554/eLife.53688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217702/
https://www.ncbi.nlm.nih.gov/pubmed/32394892
http://dx.doi.org/10.7554/eLife.53688

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