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The possible mechanisms of action of 4-aminoquinolines (chloroquine/hydroxychloroquine) against Sars-Cov-2 infection (COVID-19): A role for iron homeostasis?

The anti-malarial drugs chloroquine (CQ) and primarily the less toxic hydroxychloroquine (HCQ) are currently used to treat autoimmune diseases for their immunomodulatory and anti-thrombotic properties. They have also been proposed for the treatment of several viral infections, due to their anti-vira...

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Detalles Bibliográficos
Autores principales: Quiros Roldan, Eugenia, Biasiotto, Giorgio, Magro, Paola, Zanella, Isabella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217799/
https://www.ncbi.nlm.nih.gov/pubmed/32430286
http://dx.doi.org/10.1016/j.phrs.2020.104904