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Exploiting immune-dependent effects of microtubule-targeting agents to improve efficacy and tolerability of cancer treatment

Microtubule-targeting agents (MTAs), like taxanes and vinca alkaloids, are tubulin-binding drugs that are very effective in the treatment of various types of cancers. In cell cultures, these drugs appear to affect assembly of the mitotic spindle and to delay progression through mitosis and this corr...

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Detalles Bibliográficos
Autores principales: Serpico, Angela Flavia, Visconti, Roberta, Grieco, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217828/
https://www.ncbi.nlm.nih.gov/pubmed/32398657
http://dx.doi.org/10.1038/s41419-020-2567-0