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Association of early-onset Alzheimer’s disease with germline-generated high affinity self-antigen load

Self-antigen presentation outside the central nervous system has crucial role regarding self-proteins tolerance and autoimmunity, leading to neuroinflammation. Self-antigen with strong-binding affinity is considered to be pathogenic. We aim to investigate whether strong-binding affinity self-antigen...

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Detalles Bibliográficos
Autores principales: Huang, Poyin, Yang, Yuan-Han, Chang, Ya-Hsuan, Chang, Shu-Ling, Chou, Mei-Chuan, Lai, Chiou-Lian, Liu, Ching-Kuan, Chen, Hsuan-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217838/
https://www.ncbi.nlm.nih.gov/pubmed/32398703
http://dx.doi.org/10.1038/s41398-020-0826-6