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Association of early-onset Alzheimer’s disease with germline-generated high affinity self-antigen load
Self-antigen presentation outside the central nervous system has crucial role regarding self-proteins tolerance and autoimmunity, leading to neuroinflammation. Self-antigen with strong-binding affinity is considered to be pathogenic. We aim to investigate whether strong-binding affinity self-antigen...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217838/ https://www.ncbi.nlm.nih.gov/pubmed/32398703 http://dx.doi.org/10.1038/s41398-020-0826-6 |