Long-term use of fluoxetine accelerates bone loss through the disruption of sphingolipids metabolism in bone marrow adipose tissue

Fluoxetine is a commonly prescribed antidepressant, and the mechanisms of increased bone fragility with its long-term use remain largely unknown. Here, we show that long-term administration of fluoxetine induces the disruption of sphingolipids metabolism in bone marrow adipose tissue (BMAT)through t...

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Detalles Bibliográficos
Autores principales: Zhang, Huili, Li, Kefeng, Zhao, Yanna, Zhang, Yilan, Sun, Jiawen, Li, Shihong, Lin, Guangwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217841/
https://www.ncbi.nlm.nih.gov/pubmed/32398744
http://dx.doi.org/10.1038/s41398-020-0819-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217841/
https://www.ncbi.nlm.nih.gov/pubmed/32398744
http://dx.doi.org/10.1038/s41398-020-0819-5

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