Hepatocyte mitochondria-derived danger signals directly activate hepatic stellate cells and drive progression of liver fibrosis

Due to their bacterial ancestry, many components of mitochondria share structural similarities with bacteria. Release of molecular danger signals from injured cell mitochondria (mitochondria-derived damage-associated molecular patterns, mito-DAMPs) triggers a potent inflammatory response, but their...

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Detalles Bibliográficos
Autores principales: An, Ping, Wei, Lin-Lin, Zhao, Shuangshuang, Sverdlov, Deanna Y., Vaid, Kahini A., Miyamoto, Makoto, Kuramitsu, Kaori, Lai, Michelle, Popov, Yury V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217909/
https://www.ncbi.nlm.nih.gov/pubmed/32398673
http://dx.doi.org/10.1038/s41467-020-16092-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217909/
https://www.ncbi.nlm.nih.gov/pubmed/32398673
http://dx.doi.org/10.1038/s41467-020-16092-0

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