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Causal association of circulating cholesterol levels with dementia: a mendelian randomization meta-analysis

Prospective studies have shown that abnormally circulating cholesterol is associated with the risk of dementia. However, whether the association is causal or not remains unclear. We attempt to infer the causal association in a MR meta-analysis by using ApoE gene polymorphisms as instrument variables...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoyu, Tian, Qiuyue, Liu, Di, Geng, Tao, Xu, Xizhu, Ge, Siqi, Zheng, Deqiang, Wu, Lijuan, Song, Manshu, Hou, Haifeng, Wang, Wei, Wang, Youxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217910/
https://www.ncbi.nlm.nih.gov/pubmed/32398686
http://dx.doi.org/10.1038/s41398-020-0822-x