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Metallothioneins regulate ATP7A trafficking and control cell viability during copper deficiency and excess
Copper (Cu) is an essential, yet potentially toxic nutrient, as illustrated by inherited diseases of copper deficiency and excess. Elevated expression of the ATP7A Cu exporter is known to confer copper tolerance, however, the contribution of metal-binding metallothioneins is less clear. In this stud...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217913/ https://www.ncbi.nlm.nih.gov/pubmed/32398691 http://dx.doi.org/10.1038/s41598-020-64521-3 |