ZNF746/PARIS overexpression induces cellular senescence through FoxO1/p21 axis activation in myoblasts

Various stresses, including oxidative stress, impair the proliferative capacity of muscle stem cells leading to declined muscle regeneration related to aging or muscle diseases. ZNF746 (PARIS) is originally identified as a substrate of E3 ligase Parkin and its accumulation is associated with Parkins...

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Detalles Bibliográficos
Autores principales: Bae, Ju-Hyeon, Jeong, Hyeon-Ju, Kim, Hyebeen, Leem, Young-Eun, Ryu, Dongryeol, Park, Sang Chul, Lee, Yun-Il, Cho, Sung Chun, Kang, Jong-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217926/
https://www.ncbi.nlm.nih.gov/pubmed/32398756
http://dx.doi.org/10.1038/s41419-020-2552-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217926/
https://www.ncbi.nlm.nih.gov/pubmed/32398756
http://dx.doi.org/10.1038/s41419-020-2552-7

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