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ZNF746/PARIS overexpression induces cellular senescence through FoxO1/p21 axis activation in myoblasts
Various stresses, including oxidative stress, impair the proliferative capacity of muscle stem cells leading to declined muscle regeneration related to aging or muscle diseases. ZNF746 (PARIS) is originally identified as a substrate of E3 ligase Parkin and its accumulation is associated with Parkins...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217926/ https://www.ncbi.nlm.nih.gov/pubmed/32398756 http://dx.doi.org/10.1038/s41419-020-2552-7 |