The transcriptional regulator ZNF398 mediates pluripotency and epithelial character downstream of TGF-beta in human PSCs

Human pluripotent stem cells (hPSCs) have the capacity to give rise to all differentiated cells of the adult. TGF-beta is used routinely for expansion of conventional hPSCs as flat epithelial colonies expressing the transcription factors POU5F1/OCT4, NANOG, SOX2. Here we report a global analysis of...

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Detalles Bibliográficos
Autores principales: Zorzan, Irene, Pellegrini, Marco, Arboit, Mattia, Incarnato, Danny, Maldotti, Mara, Forcato, Mattia, Tagliazucchi, Guidantonio Malagoli, Carbognin, Elena, Montagner, Marco, Oliviero, Salvatore, Martello, Graziano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217929/
https://www.ncbi.nlm.nih.gov/pubmed/32398665
http://dx.doi.org/10.1038/s41467-020-16205-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217929/
https://www.ncbi.nlm.nih.gov/pubmed/32398665
http://dx.doi.org/10.1038/s41467-020-16205-9

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