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Context-dependent regulation of endothelial cell metabolism: differential effects of the PPARβ/δ agonist GW0742 and VEGF-A

Peroxisome proliferator activated receptor β/δ (PPARβ/δ) has pro-angiogenic functions, but whether PPARβ/δ modulates endothelial cell metabolism to support the dynamic phenotype remains to be established. This study characterised the metabolic response of HUVEC to the PPARβ/δ agonist, GW0742, and co...

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Detalles Bibliográficos
Autores principales: Faulkner, Ashton, Lynam, Eleanor, Purcell, Robert, Jones, Coleen, Lopez, Colleen, Board, Mary, Wagner, Kay-Dietrich, Wagner, Nicole, Carr, Carolyn, Wheeler-Jones, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217938/
https://www.ncbi.nlm.nih.gov/pubmed/32398728
http://dx.doi.org/10.1038/s41598-020-63900-0