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NMR insights into the pre-amyloid ensemble and secretion targeting of the curli subunit CsgA

The biofilms of Enterobacteriaceae are fortified by assembly of curli amyloid fibres on the cell surface. Curli not only provides structural reinforcement, but also facilitates surface adhesion. To prevent toxic intracellular accumulation of amyloid precipitate, secretion of the major curli subunit,...

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Detalles Bibliográficos
Autores principales: Sewell, Lee, Stylianou, Fisentzos, Xu, Yingqi, Taylor, Jonathan, Sefer, Lea, Matthews, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217966/
https://www.ncbi.nlm.nih.gov/pubmed/32398666
http://dx.doi.org/10.1038/s41598-020-64135-9