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NMR insights into the pre-amyloid ensemble and secretion targeting of the curli subunit CsgA
The biofilms of Enterobacteriaceae are fortified by assembly of curli amyloid fibres on the cell surface. Curli not only provides structural reinforcement, but also facilitates surface adhesion. To prevent toxic intracellular accumulation of amyloid precipitate, secretion of the major curli subunit,...
Autores principales: | Sewell, Lee, Stylianou, Fisentzos, Xu, Yingqi, Taylor, Jonathan, Sefer, Lea, Matthews, Steve |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217966/ https://www.ncbi.nlm.nih.gov/pubmed/32398666 http://dx.doi.org/10.1038/s41598-020-64135-9 |
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