Human multi-organ chip co-culture of bronchial lung culture and liver spheroids for substance exposure studies

Extrapolation of cell culture-based test results to in vivo effects is limited, as cell cultures fail to emulate organ complexity and multi-tissue crosstalk. Biology-inspired microphysiological systems provide preclinical insights into absorption, distribution, metabolism, excretion, and toxicity of...

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Detalles Bibliográficos
Autores principales: Schimek, Katharina, Frentzel, Stefan, Luettich, Karsta, Bovard, David, Rütschle, Isabel, Boden, Laura, Rambo, Felix, Erfurth, Hendrik, Dehne, Eva-Maria, Winter, Annika, Marx, Uwe, Hoeng, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217973/
https://www.ncbi.nlm.nih.gov/pubmed/32398725
http://dx.doi.org/10.1038/s41598-020-64219-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217973/
https://www.ncbi.nlm.nih.gov/pubmed/32398725
http://dx.doi.org/10.1038/s41598-020-64219-6

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