FcγR Binding and ADCC Activity of Human IgG Allotypes

Antibody dependent cellular cytotoxicity (ADCC) is an Fc-dependent effector function of IgG important for anti-viral immunity and anti-tumor therapies. NK-cell mediated ADCC is mainly triggered by IgG-subclasses IgG1 and IgG3 through the IgG-Fc-receptor (FcγR) IIIa. Polymorphisms in the immunoglobul...

Descripción completa

Detalles Bibliográficos
Autores principales: de Taeye, Steven W., Bentlage, Arthur E. H., Mebius, Mirjam M., Meesters, Joyce I., Lissenberg-Thunnissen, Suzanne, Falck, David, Sénard, Thomas, Salehi, Nima, Wuhrer, Manfred, Schuurman, Janine, Labrijn, Aran F., Rispens, Theo, Vidarsson, Gestur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218058/
https://www.ncbi.nlm.nih.gov/pubmed/32435243
http://dx.doi.org/10.3389/fimmu.2020.00740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218058/
https://www.ncbi.nlm.nih.gov/pubmed/32435243
http://dx.doi.org/10.3389/fimmu.2020.00740

Ejemplares similares