N-Acetyl-Seryl-Aspartyl-Lysyl-Proline Mitigates Experimental Colitis Through Inhibition of Intestinal Mucosal Inflammatory Responses via MEK-ERK Signaling

N-acetyl-seryl-aspartyl-lysyl-proline (AcSDKP) is an endogenous immunomodulatory peptide that is generated from thymosin β4 (Tβ4) through stepwise hydrolysis, involving meprin-α and prolyl endopeptidase (PREP). It is well acknowledged that AcSDKP exerts beneficial effects on multiple cardiovascular...

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Detalles Bibliográficos
Autores principales: Shi, Yingying, Zhou, Mingxia, Yan, Junkai, Gong, Zizhen, Wu, Jin, Chen, Yuanwen, Chen, Yingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218092/
https://www.ncbi.nlm.nih.gov/pubmed/32435194
http://dx.doi.org/10.3389/fphar.2020.00593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218092/
https://www.ncbi.nlm.nih.gov/pubmed/32435194
http://dx.doi.org/10.3389/fphar.2020.00593

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