Moving to CoPACaPAnA: Implementation of a continuous protein A capture process for antibody applications within an end-to-end single-use GMP manufacturing downstream process

For the first time to our knowledge the implementation of a continuous protein A capture process for antibody applications (CoPACaPAnA) embedded in an end-to-end single-use 500 L GMP manufacturing downstream process of a multispecific monoclonal antibody (mAb) using a single-use SMB system was condu...

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Detalles Bibliográficos
Autores principales: Ötes, Ozan, Bernhardt, Cathrin, Brandt, Kevin, Flato, Hendrik, Klingler, Otmar, Landrock, Katharina, Lohr, Verena, Stähler, Ralf, Capito, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218147/
https://www.ncbi.nlm.nih.gov/pubmed/32420053
http://dx.doi.org/10.1016/j.btre.2020.e00465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218147/
https://www.ncbi.nlm.nih.gov/pubmed/32420053
http://dx.doi.org/10.1016/j.btre.2020.e00465

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