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A novel multiplex qPCR assay for detection of Plasmodium falciparum with histidine-rich protein 2 and 3 (pfhrp2 and pfhrp3) deletions in polyclonal infections

BACKGROUND: Many health facilities in malaria endemic countries are dependent on Rapid diagnostic tests (RDTs) for diagnosis and some National Health Service (NHS) hospitals without expert microscopists rely on them for diagnosis out of hours. The emergence of P. falciparum lacking the gene encoding...

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Detalles Bibliográficos
Autores principales: Grignard, Lynn, Nolder, Debbie, Sepúlveda, Nuno, Berhane, Araia, Mihreteab, Selam, Kaaya, Robert, Phelan, Jody, Moser, Kara, van Schalkwyk, Donelly A., Campino, Susana, Parr, Jonathan B., Juliano, Jonathan J., Chiodini, Peter, Cunningham, Jane, Sutherland, Colin J., Drakeley, Chris, Beshir, Khalid B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218259/
https://www.ncbi.nlm.nih.gov/pubmed/32403083
http://dx.doi.org/10.1016/j.ebiom.2020.102757