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Mutations in TAC1B: a Novel Genetic Determinant of Clinical Fluconazole Resistance in Candida auris

Candida auris has emerged as a multidrug-resistant pathogen of great clinical concern. Approximately 90% of clinical C. auris isolates are resistant to fluconazole, the most commonly prescribed antifungal agent, and yet it remains unknown what mechanisms underpin this fluconazole resistance. To iden...

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Detalles Bibliográficos
Autores principales: Rybak, Jeffrey M., Muñoz, José F., Barker, Katherine S., Parker, Josie E., Esquivel, Brooke D., Berkow, Elizabeth L., Lockhart, Shawn R., Gade, Lalitha, Palmer, Glen E., White, Theodore C., Kelly, Steve L., Cuomo, Christina A., Rogers, P. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218281/
https://www.ncbi.nlm.nih.gov/pubmed/32398311
http://dx.doi.org/10.1128/mBio.00365-20