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Core N-Glycan Structures Are Critical for the Pathogenicity of Cryptococcus neoformans by Modulating Host Cell Death

Cryptococcus neoformans is a human-pathogenic fungal pathogen that causes life-threatening meningoencephalitis in immunocompromised individuals. To investigate the roles of N-glycan core structure in cryptococcal pathogenicity, we constructed mutant strains of C. neoformans with defects in the assem...

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Detalles Bibliográficos
Autores principales: Thak, Eun Jung, Lee, Su-Bin, Xu-Vanpala, Shengjie, Lee, Dong-Jik, Chung, Seung-Yeon, Bahn, Yong-Sun, Oh, Doo-Byoung, Shinohara, Mari L., Kang, Hyun Ah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218283/
https://www.ncbi.nlm.nih.gov/pubmed/32398313
http://dx.doi.org/10.1128/mBio.00711-20