Two-Step Optimization to Develop a Transdermal Film Loaded With Dapoxetine Nanoparticles: A Promising Technique to Improve Drug Skin Permeation

Dapoxetine (DPX) is an orally administered drug for the treatment of premature ejaculation (PE). One of the challenges of administering DPX orally as a tablet is its poor bioavailability (ie, 42%) due to extensive first-pass metabolism. Thus, it is vital to develop a new formulation and mode of deli...

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Detalles Bibliográficos
Autores principales: Ahmed, Tarek A., Alay, Asmaa M. S., Okbazghi, Solomon Z., Alhakamy, Nabil A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Nanotechnology and Microtechnology in Drug Delivery Systems
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218328/
https://www.ncbi.nlm.nih.gov/pubmed/32425728
http://dx.doi.org/10.1177/1559325820923859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218328/
https://www.ncbi.nlm.nih.gov/pubmed/32425728
http://dx.doi.org/10.1177/1559325820923859

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