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Modeling confinement and reversibility of threshold-dependent gene drive systems in spatially-explicit Aedes aegypti populations

BACKGROUND: The discovery of CRISPR-based gene editing and its application to homing-based gene drive systems has been greeted with excitement, for its potential to control mosquito-borne diseases on a wide scale, and concern, for the invasiveness and potential irreversibility of a release. Gene dri...

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Detalles Bibliográficos
Autores principales: Sánchez C., Héctor M., Bennett, Jared B., Wu, Sean L., Rašić, Gordana, Akbari, Omar S., Marshall, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218562/
https://www.ncbi.nlm.nih.gov/pubmed/32398005
http://dx.doi.org/10.1186/s12915-020-0759-9