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Behavioral and electrophysiological evidence for a neuroprotective role of aquaporin-4 in the 5xFAD transgenic mice model

Aquaporin-4 (AQP4) has been suggested to be involved in the pathogenesis of neurodegenerative diseases including Alzheimer’s disease (AD), which may be due to the modulation of neuroinflammation or the impairment of interstitial fluid bulk flow system in the central nervous system. Here, we show an...

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Detalles Bibliográficos
Autores principales: Abe, Yoichiro, Ikegawa, Natsumi, Yoshida, Keitaro, Muramatsu, Kyosuke, Hattori, Satoko, Kawai, Kenji, Murakami, Minetaka, Tanaka, Takumi, Goda, Wakami, Goto, Motohito, Yamamoto, Taichi, Hashimoto, Tadafumi, Yamada, Kaoru, Shibata, Terumasa, Misawa, Hidemi, Mimura, Masaru, Tanaka, Kenji F., Miyakawa, Tsuyoshi, Iwatsubo, Takeshi, Hata, Jun-ichi, Niikura, Takako, Yasui, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218576/
https://www.ncbi.nlm.nih.gov/pubmed/32398151
http://dx.doi.org/10.1186/s40478-020-00936-3