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Identification of the molecular mechanism and diagnostic biomarkers in the thoracic ossification of the ligamentum flavum using metabolomics and transcriptomics

BACKGROUND: To establish a metabolite fingerprint of ossification of the thoracic ligamentum flavum (OTLF) patients using liquid chromatography-mass spectrometry (LC-MS) in combination with transcriptomic data and explore the potential molecular mechanism of pathogenesis. RESULTS: The study cohort w...

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Detalles Bibliográficos
Autores principales: Li, Jiahao, Yu, Lingjia, Guo, Shigong, Zhao, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218621/
https://www.ncbi.nlm.nih.gov/pubmed/32404047
http://dx.doi.org/10.1186/s12860-020-00280-3