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Histone hyperacetylation mediates enhanced IL‐1β production in LPS/IFN‐γ‐stimulated macrophages

Under the condition of lipopolysaccharide (LPS)/interferon (IFN)‐γ activation, macrophage metabolism is converted from oxidative phosphorylation to glycolysis. In the present work, we analysed whether glycolysis could affect interleukin (IL)‐1β expression through altering histone acetylation levels...

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Detalles Bibliográficos
Autores principales: Dong, Zhen, Li, Ruoshui, Xu, Lei, Xin, Kaiyue, Xu, Yamei, Shi, Haiming, Sun, Aijun, Ge, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218666/
https://www.ncbi.nlm.nih.gov/pubmed/32061096
http://dx.doi.org/10.1111/imm.13183