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Phospholipid methylation regulates muscle metabolic rate through Ca(2+) transport efficiency
The biophysical environment of membrane phospholipids affects structure, function, and stability of membrane-bound proteins.(1,2) Obesity can disrupt membrane lipids, and in particular, alter the activity of sarco/endoplasmic reticulum (ER/SR) Ca(2+)-ATPase (SERCA) to affect cellular metabolism.(3–5...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218817/ https://www.ncbi.nlm.nih.gov/pubmed/32405618 http://dx.doi.org/10.1038/s42255-019-0111-2 |