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PPARγ Deficiency in Carbon Nanotube-elicited Granulomatous Inflammation Promotes a Th17 Response to a Microbial Antigen

BACKGROUND: The pathological consequences of interaction between environmental carbon pollutants and microbial antigens have not been fully explored. We developed a murine model of multi-wall carbon nanotube (MWCNT)-elicited granulomatous disease which bears a striking resemblance to sarcoidosis, a...

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Detalles Bibliográficos
Autores principales: Sanderford, Victoria, Barna, Barbara P, Barrington, Robert A, Malur, Anagha, Mohan, Arjun, Leffler, Nancy, Soliman, Eman, Thomassen, Mary Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7219023/
https://www.ncbi.nlm.nih.gov/pubmed/32405439
http://dx.doi.org/10.35248/2157-7439.20.11.541