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Pisum sativum Defensin 1 Eradicates Mouse Metastatic Lung Nodules from B16F10 Melanoma Cells

Psd1 is a pea plant defensin which can be actively expressed in Pichia pastoris and shows broad antifungal activity. This activity is dependent on fungal membrane glucosylceramide (GlcCer), which is also important for its internalization, nuclear localization, and endoreduplication. Certain cancer c...

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Detalles Bibliográficos
Autores principales: do Amaral, Virginia Sara Grancieri, Santos, Stephanie Alexia Cristina Silva, de Andrade, Paula Cavalcante, Nowatzki, Jenifer, Júnior, Nilton Silva, de Medeiros, Luciano Neves, Gitirana, Lycia Brito, Pascutti, Pedro Geraldo, Almeida, Vitor H., Monteiro, Robson Q., Kurtenbach, Eleonora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7219108/
https://www.ncbi.nlm.nih.gov/pubmed/32290394
http://dx.doi.org/10.3390/ijms21082662