MAPK pathway mutations in head and neck cancer affect immune microenvironments and ErbB3 signaling

MAPK pathway mutations affect one-fifth of head and neck squamous cell carcinoma (HNSCC). Unexpectedly, MAPK pathway aberrations are associated with remarkably long patient survival, even among patients with TP53 mutations (median ∼14 yr). We explored underlying outcome-favoring mechanisms with omic...

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Detalles Bibliográficos
Autores principales: Ngan, Hoi-Lam, Liu, Yuchen, Fong, Andrew Yuon, Poon, Peony Hiu Yan, Yeung, Chun Kit, Chan, Sharon Suet Man, Lau, Alexandria, Piao, Wenying, Li, Hui, Tse, Jessie Sze Wing, Lo, Kwok-Wai, Chan, Sze Man, Su, Yu-Xiong, Chan, Jason Ying Kuen, Lau, Chin Wang, Mills, Gordon B, Grandis, Jennifer Rubin, Lui, Vivian Wai Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7219112/
https://www.ncbi.nlm.nih.gov/pubmed/32381551
http://dx.doi.org/10.26508/lsa.201900545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7219112/
https://www.ncbi.nlm.nih.gov/pubmed/32381551
http://dx.doi.org/10.26508/lsa.201900545

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