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Inhibition of K(Ca)2 and K(v)11.1 Channels in Pigs With Left Ventricular Dysfunction

BACKGROUND: Inhibition of K(Ca)2 channels, conducting I(KCa), can convert atrial fibrillation (AF) to sinus rhythm and protect against its induction. I(KCa) inhibition has been shown to possess functional atrial selectivity with minor effects on ventricles. Under pathophysiological conditions with v...

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Detalles Bibliográficos
Autores principales: Citerni, Carlotta, Kirchhoff, Jeppe, Olsen, Lisbeth Høier, Sattler, Stefan Michael, Grunnet, Morten, Edvardsson, Nils, Bentzen, Bo Hjorth, Diness, Jonas Goldin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7219273/
https://www.ncbi.nlm.nih.gov/pubmed/32435191
http://dx.doi.org/10.3389/fphar.2020.00556