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Toll-Like Receptor 3 Activator Preconditioning Enhances Modulatory Function of Adipose-Derived Mesenchymal Stem Cells in a Fully MHC-Mismatched Murine Model of Heterotopic Heart Transplantation

BACKGROUND: Donor-specific tolerance is the ultimate goal in organ transplantation. Diverse approaches, including the use of mesenchymal stem cells (MSCs), have been investigated to induce graft tolerance. Non-stimulated MSCs showed limited regulatory functions through interaction with multiple immu...

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Detalles Bibliográficos
Autores principales: Bao, Zhiye, Li, Jingjing, Zhang, Pengju, Pan, Qi, Liu, Boqian, Zhu, Jiayi, Jian, Qian, Jia, Degong, Yi, Caiyu, Moeller, Christian J., Liu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7219555/
https://www.ncbi.nlm.nih.gov/pubmed/32366814
http://dx.doi.org/10.12659/AOT.921287