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Crystal structure of Thermus thermophilus methylenetetrahydrofolate dehydrogenase and determinants of thermostability

The elucidation of mechanisms behind the thermostability of proteins is extremely important both from the theoretical and applied perspective. Here we report the crystal structure of methylenetetrahydrofolate dehydrogenase (MTHFD) from Thermus thermophilus HB8, a thermophilic model organism. Molecul...

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Detalles Bibliográficos
Autores principales: Maiello, Fernando, Gallo, Gloria, Coelho, Camila, Sucharski, Fernanda, Hardy, Leon, Würtele, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7219735/
https://www.ncbi.nlm.nih.gov/pubmed/32401802
http://dx.doi.org/10.1371/journal.pone.0232959