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Knocking Out Non-muscle Myosin II in Retinal Ganglion Cells Promotes Long-Distance Optic Nerve Regeneration

In addition to altered gene expression, pathological cytoskeletal dynamics in the axon are another key intrinsic barrier for axon regeneration in the central nervous system (CNS). Here, we show that knocking out myosin IIA and IIB (myosin IIA/B) in retinal ganglion cells alone, either before or afte...

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Detalles Bibliográficos
Autores principales: Wang, Xue-Wei, Yang, Shu-Guang, Zhang, Chi, Hu, Ming-Wen, Qian, Jiang, Ma, Jin-Jin, Zhang, Yingchi, Yang, Bin-Bin, Weng, Yi-Lan, Ming, Guo-Li, Kosanam, Anish R., Saijilafu, Zhou, Feng-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7219759/
https://www.ncbi.nlm.nih.gov/pubmed/32320663
http://dx.doi.org/10.1016/j.celrep.2020.107537