Cargando…

The degradation-promoting roles of deubiquitinases Ubp6 and Ubp3 in cytosolic and ER protein quality control

The quality control of intracellular proteins is achieved by degrading misfolded proteins which cannot be refolded by molecular chaperones. In eukaryotes, such degradation is handled primarily by the ubiquitin-proteasome system. However, it remained unclear whether and how protein quality control de...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Hongyi, Ng, Davis T. W., Cheong, Ian, Matsudaira, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7219781/
https://www.ncbi.nlm.nih.gov/pubmed/32401766
http://dx.doi.org/10.1371/journal.pone.0232755