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Oxyphylla A Promotes Degradation of α-Synuclein for Neuroprotection via Activation of Immunoproteasome

Parkinson’s disease (PD), the second most common neurodegenerative disorder, is neuropathologically characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta (SNc) and the presence of Lewy bodies in surviving neurons. α-synuclein (α-syn) is the major component of Lewy b...

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Detalles Bibliográficos
Autores principales: Zhou, Hefeng, Li, Shengnan, Li, Chuwen, Yang, Xuanjun, Li, Haitao, Zhong, Hanbing, Lu, Jia-Hong, Lee, Simon Ming-Yuen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220298/
https://www.ncbi.nlm.nih.gov/pubmed/32489702
http://dx.doi.org/10.14336/AD.2019.0612