The obesity-induced adipokine sST2 exacerbates adipose T(reg) and ILC2 depletion and promotes insulin resistance

Depletion of fat-resident regulatory T cells (T(regs)) and group 2 innate lymphoid cells (ILC2s) has been causally linked to obesity-associated insulin resistance. However, the molecular nature of the pathogenic signals suppress adipose T(regs) and ILC2s in obesity remains unknown. Here, we identifi...

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Detalles Bibliográficos
Autores principales: Zhao, Xu-Yun, Zhou, Linkang, Chen, Zhimin, Ji, Yewei, Peng, Xiaoling, Qi, Ling, Li, Siming, Lin, Jiandie D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220368/
https://www.ncbi.nlm.nih.gov/pubmed/32426492
http://dx.doi.org/10.1126/sciadv.aay6191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220368/
https://www.ncbi.nlm.nih.gov/pubmed/32426492
http://dx.doi.org/10.1126/sciadv.aay6191

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