Novel insights into breast cancer copy number genetic heterogeneity revealed by single-cell genome sequencing

Copy number alterations (CNAs) play an important role in molding the genomes of breast cancers and have been shown to be clinically useful for prognostic and therapeutic purposes. However, our knowledge of intra-tumoral genetic heterogeneity of this important class of somatic alterations is limited....

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Detalles Bibliográficos
Autores principales: Baslan, Timour, Kendall, Jude, Volyanskyy, Konstantin, McNamara, Katherine, Cox, Hilary, D'Italia, Sean, Ambrosio, Frank, Riggs, Michael, Rodgers, Linda, Leotta, Anthony, Song, Junyan, Mao, Yong, Wu, Jie, Shah, Ronak, Gularte-Mérida, Rodrigo, Chadalavada, Kalyani, Nanjangud, Gouri, Varadan, Vinay, Gordon, Assaf, Curtis, Christina, Krasnitz, Alex, Dimitrova, Nevenka, Harris, Lyndsay, Wigler, Michael, Hicks, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220379/
https://www.ncbi.nlm.nih.gov/pubmed/32401198
http://dx.doi.org/10.7554/eLife.51480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220379/
https://www.ncbi.nlm.nih.gov/pubmed/32401198
http://dx.doi.org/10.7554/eLife.51480

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