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Bacterial-induced maternal interleukin-17A pathway promotes autistic-like behaviors in mouse offspring

Maternal immune activation (MIA) by an infection is considered to be an important environmental factor of fetal brain development. Recent animal model on MIA induced by polyinosinic:polycytidylic acid, a mimic of viral infection, demonstrates that maternal IL-17A signaling is required for the develo...

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Detalles Bibliográficos
Autores principales: Yasumatsu, Kanae, Nagao, Jun-ichi, Arita-Morioka, Ken-ichi, Narita, Yuka, Tasaki, Sonoko, Toyoda, Keita, Ito, Shoko, Kido, Hirofumi, Tanaka, Yoshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220715/
https://www.ncbi.nlm.nih.gov/pubmed/32009087
http://dx.doi.org/10.1538/expanim.19-0156