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Infertility-Causing Haploinsufficiency Reveals TRIM28/KAP1 Requirement in Spermatogonia

Spermatogenesis relies on exquisite stem cell homeostasis, the carefully balanced self-renewal and differentiation of spermatogonial stem cells (SSCs). Disturbing this equilibrium will likely manifest through sub- or infertility, a global health issue with often idiopathic presentation. In this resp...

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Detalles Bibliográficos
Autores principales: Tan, Joel H.L., Wollmann, Heike, van Pelt, Ans M.M., Kaldis, Philipp, Messerschmidt, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220855/
https://www.ncbi.nlm.nih.gov/pubmed/32302554
http://dx.doi.org/10.1016/j.stemcr.2020.03.013