SNP rs17079281 decreases lung cancer risk through creating an YY1-binding site to suppress DCBLD1 expression

Genome-wide association studies (GWAS) have identified numerous genetic variants that are associated with lung cancer risk, but the biological mechanisms underlying these associations remain largely unknown. Here we investigated the functional relevance of a genetic region in 6q22.2 which was identi...

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Detalles Bibliográficos
Autores principales: Wang, Yu, Ma, Rongna, Liu, Ben, Kong, Jinyu, Lin, Hongyan, Yu, Xiao, Wang, Ruoyang, Li, Lei, Gao, Ming, Zhou, Baosen, Mohan, Man, Yu, Herbert, Hou, Zhaoyuan, Shen, Hongbin, Qian, Biyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220863/
https://www.ncbi.nlm.nih.gov/pubmed/32231272
http://dx.doi.org/10.1038/s41388-020-1278-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220863/
https://www.ncbi.nlm.nih.gov/pubmed/32231272
http://dx.doi.org/10.1038/s41388-020-1278-4

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