Nuclear DLC1 exerts oncogenic function through association with FOXK1 for cooperative activation of MMP9 expression in melanoma

A Rho GTPase-activating protein (RhoGAP), deleted in liver cancer 1 (DLC1), is known to function as a tumor suppressor in various cancer types; however, whether DLC1 is a tumor-suppressor gene or an oncogene in melanoma remains to be clarified. Here we revealed that high DLC1 expression was detected...

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Detalles Bibliográficos
Autores principales: Yang, Xintao, Hu, Feng, Liu, Jessica Aijia, Yu, Shan, Cheung, May Pui Lai, Liu, Xuelai, Ng, Irene Oi-Lin, Guan, Xin-Yuan, Wong, Kelvin K. W., Sharma, Rakesh, Lung, Hong Lok, Jiao, Yufei, Lee, Leo Tsz On, Cheung, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220869/
https://www.ncbi.nlm.nih.gov/pubmed/32214200
http://dx.doi.org/10.1038/s41388-020-1274-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220869/
https://www.ncbi.nlm.nih.gov/pubmed/32214200
http://dx.doi.org/10.1038/s41388-020-1274-8

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