Mitigating off-target effects in CRISPR/Cas9-mediated in vivo gene editing

The rapid advancement of genome editing technologies has opened up new possibilities in the field of medicine. Nuclease-based techniques such as the CRISPR/Cas9 system are now used to target genetically linked disorders that were previously hard-to-treat. The CRISPR/Cas9 gene editing approach wields...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Hua Alexander, Pang, Jeremy Kah Sheng, Soh, Boon-Seng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220873/
https://www.ncbi.nlm.nih.gov/pubmed/32198625
http://dx.doi.org/10.1007/s00109-020-01893-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220873/
https://www.ncbi.nlm.nih.gov/pubmed/32198625
http://dx.doi.org/10.1007/s00109-020-01893-z

Ejemplares similares