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Hypoxia-induced release, nuclear translocation, and signaling activity of a DLK1 intracellular fragment in glioma

Glioblastoma multiforme is characterized in part by severe hypoxia associated with tumor necrosis. The cellular response to hypoxia can influence several properties of tumor cells associated with aggressive tumor growth, including metabolic adaptations and tumor cell migration and invasion. Here, we...

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Detalles Bibliográficos
Autores principales: Grassi, Elisa Stellaria, Pantazopoulou, Vasiliki, Pietras, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220882/
https://www.ncbi.nlm.nih.gov/pubmed/32205867
http://dx.doi.org/10.1038/s41388-020-1273-9